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Reduction of automatic pressure support based on a target respiratory frequency or mandatory rate ventilation (MRV) is available in the Taema-Horus ventilator for the weaning process in the intensive care unit (ICU) setting.

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When the patients arrived at the ICU after surgery, they were randomly assned to either: traditional weaning, consisting of the manual reduction of pressure support every 30 minutes, keeping the respiratory rate/tidal volume (RR/TV) below 80 L until 5 to 7 cm HO of pressure support ventilation (PSV); or automatic weaning, referring to MRV set with a respiratory frequency target of 15 breaths per minute (the ventilator automatiy decreased the PSV level by 1 cm HO every four respiratory cycles, if the patient's RR was less than 15 per minute).

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The primary endpoint of the study was the duration of the weaning process.

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Secondary endpoints were levels of pressure support, RR, TV (m L), RR/TV, positive end expiratory pressure levels, Fi O In the intention to treat analysis there were no statistiy snificant differences between the 53 patients selected for each regarding gender (p = 0.541), age (p = 0.585) and type of surgery (p = 0.172).


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